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SS-31
SS-31 (Elamipretide) — the mitochondrial repairman. It finds your most damaged power plants and fixes their wiring, so energy stops leaking out as cellular damage. This is the "fix the furnace" peptide.
📊 The Protocol
Vial50 mg
Mix with3 mL BAC water → makes 1 mg = 6 units
Dose30–60 units (5–10 mg) per shot
Micro-dose12 units (2 mg) daily — the burnout / fatigue stack dose
Frequency3× a week, up to once daily
WhenFasted (empty stomach), under the skin — belly or thigh
Cycle8 weeks on / 3 weeks off — always run it AFTER a MOTS-c cycle
🧮 Units made simple: your insulin syringe is marked 0–100. That whole line = 1 mL. For a 5 mg shot, draw to the 30 mark. For the 2 mg burnout micro-dose, draw to 12. A full 10 mg shot = the 60 mark. No math.
⏳ How long one bottle lasts
At 5 mg 30u~10 doses (a full 8-week cycle at 3×/week runs ~2–3 bottles)
At 2 mg 12u~25 doses — the daily micro-dose stretches it to ~3–4 weeks
At 10 mg 60u~5 doses (0.6 mL each, top of the range)
One 50 mg vial = 300 units total. Where you land depends on the goal — a light daily burnout dose lasts far longer than a full 10 mg repair shot.
💉 How to take it
Mix: add the 3 mL of BAC water slowly down the side of the vial. Swirl gently — never shake.
Store: in the fridge after mixing.
Inject: into belly fat (~2 inches from your navel) or the thigh, in a fasted state. Pinch, go straight in, push slow. Rotate the spot, fresh pin every time.
🍽️ Your diet
EatNo special diet needed — eat normally. SS-31 doesn't depend on carbs the way fat-loss peptides do.
TimingTake it fasted (empty stomach) — that's the only food rule that matters here.
💊 Take these alongside it
Prime firstRun MOTS-c 4–8 weeks BEFORE SS-31 — it builds the new mitochondria; SS-31 then protects them.
Fuel the crewNAD+ 50 mg daily — the electron acceptor that keeps energy production running.
Electron carriersCoQ10 200 mg + PQQ 20 mg daily — feed the transport chain and push new mitochondria.
Base mineralMagnesium bisglycinate 500 mg before bed.
⚠️ Watch for / red flags
Order is a law. Running SS-31 BEFORE MOTS-c "optimizes a broken system" — clear and rebuild first, then repair.
Don't over-stack. Piling on 10+ peptides at once can trigger a Herx-type reaction (feeling worse before better). Keep it lean.
Always cycle it. Constant, non-stop use makes your own maintenance systems lazy — 8 on / 3 off.
🚨 Stop & see a doctor if you get any severe or unexpected reaction after a dose.
🚫 Who should NOT take it
Pregnant, breastfeeding, or trying to conceive
You have an active cancer diagnosis — work with your doctor first
You're managing a serious medical condition or on prescription meds — clear it with your provider before starting
Under 18
🔬 How it works
SS-31 is a tiny 4-amino-acid peptide with a positive charge. Damaged mitochondria carry a negative charge on their inner membrane — so SS-31 is pulled straight to the most broken ones and ignores the healthy ones. It binds and shields cardiolipin, the fat molecule that anchors the energy-producing chain, protecting it from oxidation. The result: the power plant stops leaking energy as damage and starts running efficiently again — it makes old, worn-out biology run young.
💡 Pro Tips
Order is everything: MOTS-c FIRST, SS-31 SECOND. MOTS-c builds new power plants; SS-31 protects and repairs them. Reverse it and you're "fixing the steering wheel while driving off a cliff."
It's self-targeting — SS-31 only binds your MOST damaged mitochondria; healthy ones repel it. It "runs straight into the fire."
You may not even need it — run MOTS-c 4–8 weeks first and add SS-31 only if you still feel off. "MOTS-c is the sun; SS-31 the occasional comet."
Pairs cleanly with NAD+ and low-dose methylene blue for a full mitochondrial-energy reset — but don't turn it into a 10-peptide pile.
⚡ The Energy Lab · @hybrid.kyle
Medical Disclaimer. The Energy Lab by Hybrid Kyle provides education and information only — this is not medical advice, diagnosis, or treatment. The compounds referenced are sold for research and educational purposes and are not FDA-approved to prevent, treat, or cure any condition. Nothing here replaces a licensed healthcare provider. Always consult your doctor before starting any peptide, supplement, or protocol — especially if you're pregnant, nursing, taking medication, or managing a health condition. Individual results vary; you're responsible for your own health decisions. © 2026 Hybrid Kyle · The Energy Lab.