← All peptidesMOTS-c
The exercise-mimetic — builds brand-new mitochondria and turns your metabolism back to what it was 10–20 years ago.
📊 The Protocol
Reconstitute1 mL BAC water per 10 mg vial
DoseStart 0.25–0.5 mg, titrate to ~1–2 mg
FrequencyDaily
TimingAM, with 125–150 g low-glycemic carbs — never fully fasted/low-carb
Cycle12 weeks
💪 What it does
Builds new cellular power plants so you make more energy — the closest thing to bottling a workout. It flips the same metabolic switch as exercise, without the treadmill.
🔬 How it works
A 16-amino-acid peptide encoded in your mitochondrial DNA that flips the master energy switch AMPK → PGC-1α, driving mitochondrial biogenesis and forcing glucose into muscle without insulin.
💡 Pro tips
The startup tiredness isn't failure — it's your body tearing down old mitochondria before new ones come online. Push through ~1–2 weeks, and pair NAD+. 🩺
NEVER run it fasted or low-carb — you're forcing a glucose→fat fuel switch while starving the fuel. Run 125–150 g low-glycemic carbs/day. 🩺
Dose LOW — response is NOT linear; doubling the dose doubles side effects, not benefit. 'Anyone claiming 15 mg/day is selling bunk.' 🩺
Two modes: ~1.5–2 mg DAILY for fat loss; higher dose EVERY-OTHER-DAY on rest days for muscle. 🧪
Beats Metformin without the damage — Metformin poisons Complex I; MOTS-c hits the same AMPK pathway by signaling. 🩺